Global Certificate Pharmacokinetics Modeling: Best Practices
-- ViewingNowThe Global Certificate in Pharmacokinetics Modeling: Best Practices is a comprehensive course designed to equip learners with essential skills in pharmacokinetics (PK) modeling. This course is critical for professionals in the pharmaceutical industry, biotechnology, and research institutions who seek to understand the fundamental principles and best practices of PK modeling.
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โข Introduction to Pharmacokinetics Modeling: Overview of the fundamental concepts of pharmacokinetics, including absorption, distribution, metabolism, and elimination (ADME) processes. โข Data Analysis Techniques: Examination of various data analysis techniques, such as non-compartmental and compartmental models, used in pharmacokinetics. โข Population Pharmacokinetics (PopPK): Exploration of PopPK approaches, modeling, and simulation, with an emphasis on understanding between-subject variability and its impact on drug exposure. โข Software Tools for Pharmacokinetics Modeling: Overview of popular software tools like NONMEM, Monolix, and R, including their features, strengths, and limitations. โข Model Evaluation and Validation: Strategies for assessing the predictive performance and validity of pharmacokinetics models, including diagnostic plots, goodness-of-fit tests, and simulation-based methods. โข Model-Based Drug Development: Discussion of the role of pharmacokinetics modeling in drug development, including model-informed drug design, dose selection, and clinical trial simulation. โข Translational Pharmacokinetics: Investigation of the application of pharmacokinetics modeling in translational science, including bridging preclinical and clinical data, and understanding species differences. โข Special Populations and Pediatrics: Examination of the challenges and approaches for pharmacokinetics modeling in special populations, including pediatrics, geriatrics, and patients with renal or hepatic impairment.
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